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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Molecular chaperone therapy ： ウィキペディア英語版 Molecular chaperone therapy Molecular chaperone therapy is one of the latest pharmacological approaches to lysosomal storage diseases. It fixes defective protein as an alternative to Stop codon suppression treatment. These chaperones are minute molecules that can enter the central nervous system ( via Blood Brain Barrier). Once in the CNS, they attach to the enzyme (inactive form) and fix it so that it takes the correct functional shape. Limitation of the therapy is that it only works with certain mutations : Gaucher's disease, Fabry disease, Pompe disease and Late-onset Tay-Sachs disease. Lack of bio-marker and the potential to reduce the enzyme function if given incorrect dose are challenging aspects of current clinical trials. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Molecular chaperone therapy」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.